Desquamative gingivitis is a fairly common disorder, with a wide range of causes, most commonly lichen planus and mucous membrane pemphigoid. Non specific conditioned enlargement pyogenic granuloma tumor like gingival enlargement. Plasma cell gingivitis pcg is a rare condition of the gingiva, characterized by infiltration of plasma cells. Plasma cell gingivitis pcg is a relatively rare disease that usually occurs on the anterior maxillary and mandibular gingiva. Histopathology plasma cell gingivitis epithelium spongiosis and infiltrated with chronic inflammatory cells. Introduction plasma cell gingivitis is dense plasma cell infiltration in the gingiva secondary to hypersensitive reaction 1,2. Plasma cell gingivitis pcg is an unusual inflammatory condition characterized by dense, band. It presents clinically as a diffuse, erythematous and edematous inflammation of the gingiva that extends to the mucogingival junction that bleeds frequently, with minimal trauma. Plasma cell gingivitis pcg is a rare benign condition of the gingiva. Plasma cell gingivitis an unusual case of simultaneus. It may clinically present as isolated nodule granuloma or involve the whole gingiva. Plasmoacanthoma and plasma cell cheilitis are rare disorders of obscure etiology characterized by a plasma cell infiltrate.
Although the etiology may be unknown, this is believed to be a hypersensitivity reaction in some cases. Plasma cell gingivitis is a rare benign condition typified by nonneoplastic infiltrate of plasma cell into the gingival connective tissue. Plasma cell gingivitis associated with inflammatory. Plasma cell gingivitis may produce the swelling of the. Cheilitis, gingivectomy, hypersensitivity, plasma cell gingivitis. Various synonyms of plasma cell gingivitis are atypical gingivostomatitis, idiopathic gingivostomatitis, allergic gingivostomatitis, and plasma cell gingivostomatitis 1. Plasma cell gingivitis pgc is a rare disease of gingival tissues which is difficult to treat. Pdf plasma cell gingivitis pcg is a rare condition of the gingiva, characterized by in fi ltration of plasma cells. We present the case of a yearold girl who had pcg with an erythematous congestive plaque on the anterior maxillary gingiva for 4 years. Case report plasma cell gingivitis with severe alveolar. Sole involvement of the gingiva is not uncommon and is frequently misdiagnosed as inflammatory periodontal disease.
Plasma cell gingivitis pcg is a rare condition of the gingiva which is characterized by massive infiltration of plasma cells into the underlying subepithelial connective tissue. The present case is of an 18yearold male patient suffering from gingival enlargement along with cheilitis. Identified as an allergic reaction to a component of chewing gum, such as cinnamon or mint, it can also be caused by clove, or other herbal products in toothpaste, red peppers, chewing gum of khat leaves. Plasma cell gingivitis europe pmc article europe pmc. Plasma cell gingivitis, which is also called atypical gingivitis or plasma cell gingivostomatitis, is a rare benign inflammatory condition of unknown aetiology. Plasma cell gingivitis with severe alveolar bone loss.
Desquamative gingivitis an overview sciencedirect topics. Gingivitis has been classified by clinical appearance eg, ulcerative, hemorrhagic, necrotizing, purulent, etiology eg, druginduced, hormonal, nutritional, infectious, plaqueinduced, and. The conversion to a b cell lesion does not appear to occur. An 80yearold woman presented with a verrucous, fleshy, skin colored plaque over lips, gingiva, and the palate and painful swallowing for over a period of 6 months. Clinical signs of gingivitis either do not appear as plaque accumulates, or they are greatly delayed in children, and the inflammatory infiltrate consists mostly of t lymphocytes. Plasma cell gingivitis pcg is a rare benign condition of the gingiva characterized by sharply demarcated erythematous and edematous gingivitis often extending to the mucogingival junction. Plasma cell gingivitis a case report and literature. Plasma cell gingivitis pcg is a rare condition characterized by diffuse and massive infiltration of plasma cells into the subepithelial gingival tissue. Hypersensitivity reaction due to antigen is considered as primary etiological factor. As clinical findings in this patient, the peripheral region of the upper and lower gingivae was swollen and painful. Further, its association with chelitis is rare, only few cases have been reported and the condition with this presentation poses a diagnostic dilemma. Plasma cell gingivitis is a rare benign condition of the gingiva characterized by sharply demarcated erythematous and edematous gingivitis often extending to the mucogingival junction. The etiology is largely unknown, and it is thought to be due to a hypersensitivity reaction to an allergen. A rare case of plasma cell gingivitis with cheilitis.
Gingivitis and the periodontal microflora differ in children and adults. Plaque control and conventional periodontal therapy alone will not cure this disease. Plasma cell gingivitis is considered to be a rare condition of gingiva and represents a hypersensitive reaction with predominant plasma cell. The diagnostic workup includes comprehensive history taking, examination and laboratory tests to rule. Clinically, it appears as gingival enlargement with erythema and swelling of the attached and free gingiva and is not associated with any loss of attachment. The diagnosis is based on comprehensive history taking, clinical examination and appropriate.
Plasma cell gingivitis related to the use of herbal toothpaste. This report outlines a case of plasma cell gingivitis which may have been brought on by the use of red peppers in. The clinical diagnosis was gingival hypertrophy, and primary. Introduction plasma cell gingivitis is an uncommon benign inflammatory condition of the gingiva which is considered to arise as a hypersensitivity reaction to certain allergens. Clinically it appears as a diffuse reddening and edematous swelling. Plasma cell gingivitis among herbal toothpaste users.
Introduction plasma cell gingivitis which is also called atypical gingivitis or plasma cell gingivostomatitis, is a rare benign inflammatory condition of unknown aetiology. Plasma cell gingivitis is a rare benign condition of the gingiva characterised by sharply demarcated erythaematous and oedematous gingiva often extending up to the muco gingival junction. Plasma cell gingivitis which affects the gingiva, the palatal mucosa and the laryngeal cords. Dentists are of the opinion that i have plasma cell gingivitis and need an operation, which i am not keen on. The importance of this lesion is that it may cause severe gingival inflammation, discomfort, and. This benign condition is characterized by gingival erythema and edema. It has a higher rate of reoccurrence and needs a detailed and careful analysis of etiology. Pdf plasma cell gingivitis thomas sollecito academia. Full text pdf 3363k abstracts references11 we describe a case of plasma cell gingivitis that occurred in the upper and lower gingivae of a 38yearold man. Plasma cells are also associated with diseases such as plasma cell pododermatitis and plasma cell chondritis the lesions have a tendency to ulcerate and bleed. These include rare cases of extramedullary plas macytoma, plasmacytosis of the gingiva,1 plasmacell gingivitis,2 and plasma cell granuloma.
Unusual cases of plasma cell gingivitis periodontist. It manifests as extreme redness, swelling and gum tissue enlargement with propensity for bleeding, accompanied by extensive infiltration of plasma cells in the lamina propria. Generalized aggressive periodontitis associated with a. Plasma cell gingivitis pcg is a rare condition of the gingiva, characterized by in fi ltration of plasma cells.
Occasionally, the lesion became increasingly swollen and painful and. Plasma cell gingivitis with aggressive periodontitis. Gingivitis is an inflammatory process limited to the mucosal epithelial tissue surrounding the cervical portion of the teeth and the alveolar processes. Plasma cell gingivitis pcg is a rare inflammatory disease of the gums, which is defined by plasma cell infiltration into subepithelial tissue. Plasma cell gingivitis is a rare condition characterized by diffuse and massive infiltration of plasma cells into the subepithelial gingival tissue. Diagnosis of plasma cell gingivitis from a dental referral of. Plasma cell gingivitis pcg is a rare condition of the gingiva, characterized histopathologically by infiltration of plasma cells in connective tissue.
In cats, it causes anorexia, halitosis, excessive salivation and weight loss, often with associated gingivitis and stomatitis. Plasma cell gingivitis pcg, an infrequent benign inflammatory condition of unknown etiology, is a type of plasma cell orificial mucositis, which includes a wide. Plasma cell gingivitis is a rare condition, appearing as generalized erythema redness and edema swelling of the attached gingiva, occasionally accompanied by cheilitis lip swelling or glossitis tongue swelling. Plasma cell stomatitis is characterised by painful proliferative lesions on the palatoglossal folds and arches. Plasma cell gingivitis is an uncommon inflammatory condition of the gingiva, characterized by plasma cell infiltration in the gingiva. Plasma cell gingivitis pcg is a rare condition of gingiva marked by diffuse plasma cells into the subepithelial gingival tissue. Plasma cell gingivitis pcg, an infrequent benign inflammatory condition of unknown etiology, is a type of plasma cell orificial mucositis, which includes a wide spectrum of conditions. As the name suggests it is diffuse and massive infiltration of plasma cells into the subepithelial gingival tissue. The lesion was believed to have been largely eliminated by removing the allergens from the products. It is difficult to diagnose your condition without examining you, but if you have any underlining periodontal disease, then the disease should be treated appropriately.
It is called plasma cell gingivitis where the gingiva gums are involved, plasma cell cheilitis, where the lips are involved, and other terms such as plasma cell orifacial. The etiology is largely unknown, but it is thought to be. Plasma cell gingivitis is a rare condition characterized by diffuse and massive infiltration of plasma cells into the subepithelial connective tissue. Its etiology is unknown, but hypersensitivity reaction has been proposed.
It is marked by a dense infiltrate of normal plasma cells separated into aggregates by strands of collagen. The etiologic agent must be identified and the substance eliminated from use. A recent article by joshi and shukla 2015 reported a patient with plasma cell gingivitis. The etiology is largely unknown, but it is thought to be due to a hypersensitivity. Plasma cell gingivitis mimicking granulomatous disease. The associated cheilitis has dramatically reduced after treatment of the gingival lesion. It presents clinically as a diffuse, erythematous and papillary lesion of the gingiva, which frequently bleeds, with minimal trauma. Plasma cell gingivitis is an uncommon condition, characterised by a sharply demarcated, erythematous and oedematous gingivitis, often extending to the mucogingival junction. Plasma cell gingivitis related to the use of herbal. Plasma cell gingivitis is a rare benign condition which presents as an enlargement of the gingiva, characterised by dense infiltration of plasma cells in the subepithelial connective tissue. Fulltext pdf histopathological analysis of unilateral condylar hyperplasia. Discontinuation of the offending products promoted an elimination of the gingivitis. Plasma cell gingivitis is a condition that often consists of a mild enlargement of the gums at the marginal areas which may extend to the gums attached over the alveolar bone.
Plasma cell gingivitis joshi c, shukla p j indian soc. In most of the cases the underlying etiology is allergic reaction to a foreign substance such as cinnamon, chewing gum, spices or dentifrices. The condition is also known as atypical gingivitis, plasma cell gingivostomatitis and plasma cell granuloma. Plasma cell gingivitis is a disorder first described in the 1960s and was believed to be caused by an allergic reaction to flavored chewing gum and toothpaste. The lamina propria revealed extremely dense infiltration of chronic inflammatory cell infiltrate that was composed predominantly of plasma cells, few russel bodies and numerous dilated vascular channels were consistently seen throughout the stroma tablefig4,5. Also, some isolated generalized gingival lesions such as plasma cell gingivitis, plaque induced gingival hyperplasia, scurvy. Plasma cell gingivitis kandwal a et al 187 association of pcg and chelitis is very rare and proper involvement of periodontist and dermatologist is necessary to treat the condition. A rare case of plasma cell gingivitis with cheilitis hindawi. A recent article by joshi and shukla 2015 reported a patient with plasma cell gingivitis after prolonged use of herbal toothpowder. The histologic appearance was compatible with plasma cell gingivitis. Plasma cell infiltration is also found in other organs of the system like the lung, bronchi, liver, kidney, spinal cord, intracranial space, thyroid gland and stomach. Plasma cell gingivitis is a rare condition, appearing as generalized erythema redness and.
It presents clinically as a diffuse, erythaematous and papillary lesion of the gingiva, which frequently bleeds, with minimal trauma. Case report a rare case of plasma cell gingivitis with. Pdf plasma cell gingivitis pcg, an infrequent benign inflammatory condition of unknown etiology, is a type of plasma cell orificial mucositis, which. Plasma cell gingivitis associated with dry flower buds of clove. Clinical differential diagnosis may include any of the desquamative gingivitis, such as erythematouserosive lichen planus, autoimmune.